Karyopharm Therapeutics is a clinical-stage pharmaceutical company developing drugs for the treatment of cancer and other major diseases.
Karyopharm Therapeutics is a biopharmaceutical company with a focus on the development of novel drugs for the treatment of cancer, inflammation, and diseases related to cell proliferation. Karyopharm Therapeutics is developing small molecule drugs that will modulate the activity of critical pathways in cancer, inflammation, and cell proliferation (e.g. FOXO, NFкB, P53, pRB) by targeting the nuclear pore complex machinery, which controls the import and export of proteins between the nucleus and cytoplasm. To successfully control transport through the nuclear pore complex, the company will use its unique technology platform, developed by Sharon Shacham, to identify novel small molecules, optimize them into clinical candidates, and evaluate them in subsequent human clinical studies.
Announced Date | Round | Money Raised | Number of Investors | Lead Investors | Post Valuation | |
---|---|---|---|---|---|---|
Dec 5, 2022 | Post-IPO Equity | $165M | 9 | Avidity Partners | — | Detail |
Mar 6, 2020 | Post-IPO Equity | $172.50M | — | — | — | Detail |
Jun 30, 2014 | Post-IPO Equity | $111M | — | — | — | Detail |
Nov 6, 2013 | IPO | $108.80M | — | — | — | Detail |
Jul 31, 2013 | Series B | $19M | 3 | Foresite Capital | — | Detail |
Investor Name | Lead Investor | Funding Round |
---|---|---|
Avidity Partners | Yes | Post-IPO Equity |
Foresite Capital | Yes | Series B |
Chione | Yes | Series A |
Multiple Myeloma Research Foundation | Yes | Grant |
Adage Capital Management | — | Post-IPO Equity |
Armistice Capital | — | Post-IPO Equity |
HealthCor Partners | — | Post-IPO Equity |
Heights Capital Management | — | Post-IPO Equity |
Marshall Wace | — | Post-IPO Equity |
Rubric Capital Management | — | Post-IPO Equity |