Manuel's career has been focused on supporting large collaborations through technological innovation. He has led critical data-management, big data and machine-learning initiatives for the largest and most complex scientific instrument ever built (CERN LHC). In addition, he has collaborated with NASA-JPL, Fermilab (U.S. Dept. of Energy) and GSI, among others. He has contributed, as a guest lecturer, to the Executive Program at ESADE Business School, and has advised international companies such as Oracle, BMW, Caixa, Gassco, Eni, UPS.